Researchers of Japan have identified a protein that plays an important role in providing regular hunger signals to the brain and in metabolism. Research done on rats found that when a protein called XRN1 in the forebrain is reduced, their appetite increases, and they become obese.
According to Professor Tadashi Yamamoto, a scientist at the Okinawa Institute of Science and Technology Graduate University in Japan, fundamentally the cause of obesity is an imbalance in the adjustment of food and the energy generated from it. This research has been published in the science journal 'IScience'. At present, obesity is a major cause of public health concern. More than 650 million adults worldwide are obese. Due to excessive weight gain, many other diseases related to it are also taking the form of the epidemic, such as type-2 diabetes, cancer, etc.
Researcher Dr. Akiko Yanagiya said that we have not yet understood how the coordination between the brain and the digestive system is made. How the brain and other parts of the body such as the pancreas, liver, and adipose tissue work together.